We compare how intrinsic and recurrent temporal adaptation mechanisms in deep neural networks affect object recognition under challenging conditions. We find intrinsic adaptation is superior for recognizing simple, high-contrast objects in noise, whereas recurrent adaptation better maintains coherence under dynamic occlusion and improves novelty detection. These results indicate that robust object recognition likely depends on multiple parallel adaptation strategies.
Apr 3, 2025
We examine how cholinergic interneuron (CIN)-specific deletion of D2 receptors affects dopamine (DA) and acetylcholine (ACh) dynamics in response to repeated psychostimulant exposure. Using dual-color photometry, we find that mice lacking D2 receptors on CINs fail to sensitize DA and ACh signaling but still develop behavioral sensitization, albeit more slowly. This suggests behavioral sensitization occurs independently from neuromodulatory sensitization driven by CIN-expressed D2 receptors.
Apr 3, 2025